WebJul 22, 2024 · A Double-blind, Randomized, Controlled Trial of ATI-450 in Patients With Moderate-severe COVID-19: Actual Study Start Date : July 20, 2024: Actual Primary Completion Date : February 25, 2024: Actual Study Completion Date : June 1, 2024: Resource links provided by the National Library of Medicine. WebMar 20, 2024 · ATI-450 prevents inflammation and joint destruction in inflammatory arthritis in rats. ATI-450 selectively blocks p38α MAPK activation of the proinflammatory kinase MK2 while sparing p38α ...

ATI-450 on Covid19 - Clinical Trials Registry - ICH GCP

WebJan 30, 2024 · This is a Phase 2, randomized, investigator and patient-blind, sponsor-unblinded, parallel group, placebo-controlled study to investigate the safety, tolerability, … WebJan 19, 2024 · About ATI-450. ATI-450 is an investigational oral mitogen-activated protein kinase-activated protein kinase 2 (MK2) inhibitor. This mechanism potentially leads to the inhibition of multiple ... signification showroom

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WebJan 31, 2024 · A Phase 2a, Randomized, Double-blind, Placebo-controlled Study to Investigate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ATI-450 vs Placebo in Patients With Moderate to Severe HS: Actual Study Start Date : December 29, 2024: Actual Primary Completion Date : December 23, 2024: Actual Study … WebJan 20, 2024 · Per the company, subjects were randomized in a 3:1 ratio in the above study and received either ATI-450 (50 mg twice daily) or placebo in combination with methotrexate for a period of 12 weeks. WebThese investigational drugs were developed internally utilizing KINect®, our proprietary drug discovery platform the purple pebble photography