WebJul 8, 2024 · Tonicity-responsive enhancer binding protein (TonEBP) is a widely expressed transcription factor and is important in the regulation of inflammatory cytokines. Here, we have identified TonEBP expression in the hypothalamus, which is particularly high in proopiomelanocortin (POMC) neurons. WebAug 6, 2024 · Tonicity-responsive enhancer binding protein (TonEBP or NFAT5) is a regulator of cellular adaptation to hypertonicity, macrophage activation and T-cell …
NFAT5 - Wikipedia
WebNov 29, 2024 · Tonicity-responsive enhancer-binding protein (TonEBP) promotes diabetic neuroinflammation. However, the precise role of TonEBP in the diabetic brain is … shudder comedy horror movies
High blood sugar may blunt the protective benefits of FXR for the ...
WebBackgroud: Diabetic nephropathy is the most common renal complication of diabetes and the leading cause of end-stage renal disease. many factors lead to the occurrence of this disease. However, little attention has been paid to the effect of water deficiency on DN. This study focused ... WebFeb 1, 2024 · Among these, the transcription factor tonicity-responsive enhancer binding protein (TonEBP) and its target osmoprotective genes, including aldose reductase and heat shock protein 70 (HSP70), represents the most important protective mechanisms ( Lee et … WebAug 20, 2024 · The endoplasmic reticulum (ER) stress response and autophagy are important cellular responses that determine cell fate and whose dysregulation is implicated in the perturbation of homeostasis and diseases. Tonicity-responsive enhancer-binding protein (TonEBP, also called NFAT5) is a pleiotropic stress protein that mediates both … the otherist broad street