H2a histone family member x

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August undefined, 2024

WebMar 31, 2016 · Anti-gamma H2A.X (phospho S139) antibody (ab2893) Datasheet SDS Reviews ( 36) Submit a question References (321) +9 Key features and details Rabbit polyclonal to gamma H2A.X (phospho S139) Suitable for: ICC/IF, WB Reacts with: Mouse, Rat, Human Isotype: IgG Get better batch-to-batch reproducibility with a recombinant … WebBackground: Carcinogenesis occurs when the cell cycle is compromised. Chromatin licensing and DNA replication factor 1, geminin, and γ-H2A histone family member X …

Phospho-gamma-H2AX (Ser139) Polyclonal Antibody - Thermo Fisher Scientific

WebOverview Product name Anti-gamma H2A.X (phospho S139) antibody [9F3] See all gamma H2A.X primary antibodies Description Mouse monoclonal [9F3] to gamma H2A.X (phospho S139) Host species Mouse Tested applications Suitable for: Flow Cyt, WB, IHC-P more details Species reactivity Reacts with: Mouse, Rat, Human, Chinese hamster Immunogen WebHuntington disease (HD) is a progressive neurodegenerative disease that affects 30,000 individuals in North America. Treatments that slow its relentless course are not yet … herniation of the iris

Immunohistochemical assessment of chromatin licensing and DNA …

WebAnti-gamma H2A.X (phospho S139) antibody See all gamma H2A.X primary antibodies Description Rabbit polyclonal to gamma H2A.X (phospho S139) Host species Rabbit Specificity Using IF, this antibody was shown to bind to a non-nuclear location in Hela cells. Tested applications Suitable for: IHC-P, ICC/IF, WB more details Species reactivity WebApr 14, 2024 · During the pachytene stage in mammalian meiosis, the X and Y chromosomes remain largely unsynapsed outside the pseudoautosomal region, while autosomes are fully synapsed. Then, the sex chromosomes are compartmentalized into a “sex body” in the nucleus and are subjected to meiotic sex chromosome inactivation … WebThe H2A histone family member X (usually abbreviated as H2AX) is a type of histone protein from the H2A family encoded by the H2AFX gene. An important phosphorylated … herniation of the brain through the skull

E6 Oncoproteins from High-Risk Human Papillomavirus Induce ...

H2a histone family member x

Anti-Histone H2A.X Antibody serum, Upstate® Sigma-Aldrich

WebSep 2, 2024 · H2A Histone Family Member X (H2AX) Is Upregulated in Ovarian Cancer and Demonstrates Utility as a Prognostic Biomarker in Terms of Overall Survival H2A … WebPhosphorylation of H2A histone family member X (H2AX) to γ-H2AX is induced by DNA double-strand breaks and is associated with the development of colorectal cancer …

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WebH2A.X. a histone isoprotein with a conserved C-terminal sequence, is encoded by a novel mRNA with both DNA replication type and polyA 3' processing signals. Mannironi, C., Bonner, W.M., Hatch, C.L. Nucleic Acids Res. (1989) [ Pubmed] Novel genotoxicity assays identify norethindrone to activate p53 and phosphorylate H2AX. H2A histone family member X (usually abbreviated as H2AX) is a type of histone protein from the H2A family encoded by the H2AFX gene. An important phosphorylated form is γH2AX (S139), which forms when double-strand breaks appear. In humans and other eukaryotes, the DNA is wrapped … See more H2AX becomes phosphorylated on serine 139, then called γH2AX, as a reaction on DNA double-strand breaks (DSB). The kinases of the PI3-family (Ataxia telangiectasia mutated, ATR and DNA-PKcs) are … See more H2AX has been shown to interact with: • BARD1, • BRCA1 • Bloom syndrome protein, See more • Redon C, Pilch D, Rogakou E, Sedelnikova O, Newrock K, Bonner W (Apr 2002). "Histone H2A variants H2AX and H2AZ". Current Opinion in Genetics & Development. 12 … See more DNA damage response The histone variant H2AX constitutes about 2-25% of the H2A histones in mammalian chromatin. When a … See more An assay for γH2AX generally reflects the presence of double-strand breaks in DNA, though the assay may indicate other minor phenomena as well. On the one hand, overwhelming evidence supports a strong, quantitative correlation between γH2AX foci formation and … See more

WebDec 11, 2024 · Nucleosomes are the basis of chromatin organization in eukaryotes. Nucleosomes are assembled by the sequential association of two histone H3–H4 dimers and two histone H2A–H2B to form an octameric protein complex that wraps about 147 base-pairs of DNA [].Nucleosome assembly requires the aid of protein chaperones that … WebSep 2, 2024 · H2A Histone Family Member X (H2AX) Is Upregulated in Ovarian Cancer and Demonstrates Utility as a Prognostic Biomarker in Terms of Overall Survival by …

WebMar 1, 2009 · Histone H2AFX mRNA (NM_002105) has 1594 bp and is synthesized in G1 as well as S phase. It is known to have two forms of transcript; one having a polyA tail (1651 bp) and another having a … WebHistone H2A.X Antibodies Antibodies that detect Histone H2A.X can be used in several scientific applications, including Western Blot, Immunohistochemistry, …

WebAnti-Ubiquityl Histone H2A.X (Lys119) Antibody is a rabbit polyclonal antibody for detection of Ubiquityl Histone H2A.X (Lys119) also known as H2AXK119Ub, Histone H2A.X Ubiquityl K119) & has been validated in WB, IP, ICC. Immunocytochemsitry Analysis: 1:500 dilution from a representative lot detected Histone H2A.X in RAW264.7 and NIH/3T3 cells.

WebAnti-Histone H2A (acidic patch) Antibody is a Rabbit Polyclonal Antibody for detection of Histone H2A (acidic patch) also known as histone 2-H2ac, histone IIa & has been validated in ChIP & WB. Immunofluorescence: Recommend Anti-phospho-Histone H2A.X (Ser139), clone JBW301, catalog #05-636. Research Category Epigenetics & Nuclear … herniation of the ureterhttp://www.cnreagent.com/show1001180/product_92872.html maximus health care jobWebAnti-gamma H2A.X (phospho S139) antibody [EP854 (2)Y] See all gamma H2A.X primary antibodies Description Rabbit monoclonal [EP854 (2)Y] to gamma H2A.X (phospho S139) Host species Rabbit Tested applications Suitable for: IP, IHC-P, WB, ICC/IF, Dot blot more details Species reactivity Reacts with: Mouse, Rat, Human Predicted to work with: Sheep maximus healthcare pa